Cause and Risk Factors Of Crohn’s Disease
The exact cause of Crohn’s Disease is not known. It is believed to be caused by immune dysfunction triggered by infection. While the immune system is fighting the invading bacteria or virus, an abnormal immune response occurs by attacking the digestive tract. Crohn’s Disease is more common in people who have family members with the disease, indicating that heredity seems to play a role, too.
Risk Factors of Crohn’s Disease
Crohn’s disease usually begins before the age of 30, but it can occur at any age.
There is higher risk if you have a close relative, such as a parent, sibling or child, with the disease.
Race or Ethnicity
Whites have the highest risk, but it can occur in any race. The risk is even higher if you are of Ashkenazi Jewish descent.
Smoking is associated with increased risk for Crohn’s Disease. Smoking also leads to greater risk of surgery and other more severe diseases.
Nonsteroidal Anti-inflammatory Medications (NSAIDs)
NSAIDs can lead to inflammation of the bowel, making Crohn’s disease worse. NSAIDs include ibuprofen, aspirin, Diclofenac and Naproxen.